
38 Agilent 1100 Series Valves
4 Valve Applications
Sample enrichment and Sample stripping
Sample enrichment and Sample stripping
Sample enrichment and sample stripping methods can be used to separate
samples from complex matrices, such as biological fluids, food extracts or
wastewater. This might be necessary to avoid interference of the matrix during
separation and detection or even damage of the column. You can use the 1100
Series 2 position/ 6 port valve (G1158A) to automate these techniques for LC
and LC/MS analysis.
Sample enrichment
Sample enrichment is used to increase the sensitivity and to remove the
sample matrix. The technique is displayed in Figure 21 on page 38. This
technique allows the injection of large volumes onto the precolumn, where the
sample matrix is separated from the analytes in order to increase sensitivity.
Figure 21 Sample enrichment (schematic setup)
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